Description: 7-KETO DHEA is an analog to DHEA which cannot be metabolized to active adrogenic or estrogenic hormones but retains and enhances the immunologic, memory enhancing and thermogenic effects of DHEA. DHEA is a hormone produced by the adrenal glands which is converted into a variety of other hormones including androgens and estrogen (male and female sex hormones) and corticosteroids. Supplemental DHEA is extracted in sterol form (e.g. diosgenin) from wild yams and engineered in laboratory conditions. Male humans produce 1 to 2 mg of DHEA daily and women 10 to 20% less. Human DHEA levels tend to decline with age.
Method of Action: DHEA has various effects throughout the body on cardiovascular, immune and nervous systems. Causes more rapid decline of membrane potential in liver inducing a proton leak or slip, which may contribute to the enhanced thermogenesis noted with DHEA supplementation.
Indications and Usage: Decline (esp. age-associated) in immune response; Weight loss; Memory difficulties including Alzheimer's Disease and declines in learning and retention; May also be helpful with: Mild to moderate depression; Tiredness and lethargy; High LDL cholesterol; Age-Associated Memory Problems; Insulin Regulation; Balancing DI-IFA and cortisol levels; Osteoporosis; Reversal of scopolamine-induced amnesia.
Contraindications: Do not use this product if you are pregnant or lactating without first seeking advice from your physician. Post-menopausal women should not use DHEA.
Dosage and Administration: Baseline DHEA levels should be check with blood test prior to supplementation. DHEA is produced in the human body during the morning hours and supplementation is advised during this time. Dosage is highly individual. Supplementation usually begins after age 40. Starting doses of 5-10 mg. with a therapeutic range between 10 and 50 mg daily in divided doses are standard. Use only 7-KETO DHEA not DHEA . Should be taken with 250 mg of Vitamin-E to attenuate mild oxidative stress on heart muscle (comparable to aerobic exercise).
Clinical Effect In: Both immediate and long-term effects.
Adverse Reactions: Short-term clinical and anatomical pathology studies have found no changes in laboratory values including dihydrotestosterone, estradiol, cortisone and insulin in animal and human studies with 7-KETO DHEA even at very high dosages. No long-term human studies are currently available. Supplementation could theoretically lower body's own production of DHEA. Infrequent reported side effects include: Acne and excessive oiliness, unwanted hair growth (women only), irritability or mood changes. overstimulation of insomnia, fatigue or low energy, aggressiveness, headaches, nervousness, deepening of voice, menstrual irregularity. If you suspect that an herb or other supplement is making you sick, call the FDA's MedWatch hotline at 800-332-1088 or contact the agency via its website at http://www.fda.gov/medwatch.
Known Interactive Effects: Complex interactive effects can be anticipated with all hormonal supplementation but no specific information available at this time. Will affect other hormonal therapies (e.g. birth control, estrogen replacement, thyroid medication). Due to blood thinning effect dosage of other anticoagulant medication may need to be adjusted. Do not use with stimulants such as diet pills or nutrients such as ephedra and guarana.
Additional Considerations: Natural yam extracts which have not been synthesized in a laboratory are ineffective.
Warnings: The information above is provided for educational purposes and may not be construed as a medical prescription or as a substitute for the advice of your physician. Do not use this product without first consulting your physician especially if you are pregnant or lactating. Be advised that some herbs and dietary supplements can cause severe allergic reactions in some individuals and may also have an adverse result in conjunction with other medications, or treatments. You should regularly consult your physician in matters regarding your health and particularly in respect to symptoms and conditions which may require diagnosis or medical attention. Reevaluate use of this product after 6 months.