Method of Action: Contains volatile oils called gingerols and shogaol which act as antispasmodic and antinausea agents.
Indications and Usage: Gastrointestinal Discomfort; Motion Sickness; Nausea. Useful in pregnancy. Found to be similarly effective to metoclopramide hydrochloride to treat post-operative nausea and vomiting. Promotes secretion of saliva and gastric juices. Strengthens heart muscle.
Contraindications: Do not use this product if you are pregnant or lactating without first seeking advice from your physician. Possible mutagenesis in Eschericha coli has been identified making non-acute use inadvisable. Ginger is a potent inhibitor of thromboxane synthetase which prolongs bleeding time making ginger problematic for extended use in surgical or childbirth situations. Should not be used concomitantly with warfarin sodium.
Dosage and Administration: Two to three 500 mg capsules of ciry powdered ginger in capsule form one half hour prior to nausea causing activity. One to two additional 500 mg capsule every four to six hours. For morning sickness - 250 mg capsule three times daily.
Clinical Effect In: 30 minutes
Adverse Reactions: May prolong postoperative bleeding, aggravate gallstones and cause heartburn. Found to activate p450 liver enzymes resulting in increase in control cytochrome (isozymes 2E 1 and 4A) activity during in vitro testing. If you suspect that an herb or other supplement is making you sick, call the FDA's MedWatch hotline at 800-332-1088 or contact the agency via its website at http://www.fda.gov/medwatch.
Known Interactive Effects: None known.
Additional Considerations: In studies effectiveness of ginger was greater then Dramamine for treatment of motion sickness.