Description: Used for centuries in Ayurvedic and Chinese medicines. A tasteless and odorless member of the parsley family. Centella is the most potent variety of gotu kola found in Asia, India, Sri Lanka, parts of China, western South Sea Islanda, Madagascar, South Africa, southeast U.S., Mexico, Venezuela, Columbia and eatern S. America. Green leaves are harvested in fall and air dried, then extracted in water/acetone mixture, filtered and concentrated.
Method of Action: Primary mode of action appears to be on connective tissue development. Asiaticosides and other tri-terpines stimulate the reticuloendothelial system where, new blood cells are formed, iron is metabolized, fatty materials are stored, and immune responses and inflammation are initiated.
Indications and Usage: Exerts a relaxant effect on central nervous system while decreasing general fatigue. Useful in treating insomnia and, possibly, difficulties with memory and concerntration. In higher doses can act as a sedative. May have utility in treating colds and upper respiratory problems including congestion and asthmatic conditions. May have diuretic effect. Used traditionally as a blood purifyer, tonic and diuretic. Also, stimulates keratinization, the building of new skin around wounds. Asiaticosides also stimulate the synthesis of lipids and proteins needed for healthy skin. Gotu Kola also strengthens connective tissue surrounding veins. Can be useful in healing of skin and mucus membrane infections including leprosy and tuberculosis.
Contraindications: None known. Do not use this product if you are pregnant or lactating without first seeking advice from your physician.
Dosage and Administration: 0.33 to 0.68 grams taken up to three times daily standardized to 10% asiaticosides. For topical preparations 1% applied twice daily. For insomnia take 0.5 teaspoon in cup of water 20 minutes prior to bedtime. Do not take for more than two weeks without a break.
Clinical Effect In: 20-30 minutes.
Adverse Reactions: Use of this herb may cause a rash. Discontinue use if rash develops. FDA rates this herb as having undefined safety. Liver and blood mononuclear toxicity has been found for this product during in vitro testing. Found to inactivate p450 liver enzymes resulting in a decrease in control cytochrome (isozymes 2E1 and 4A) activity. If you suspect that an herb or other supplement is making you sick, call the FDAs MedWatch hotline at 800-332-1088 or contact the agency via its website at http://www.fda.gov/medwatch.
Known Interactive Effects: Adrenocortical responsiveness to gotu kola may be reduced by the use of amphotericin B. the tannin in gotu kola may potentiate antibiotic activity of echinacea. Milk or cream will tend to inactivate tannins in gotu kola. May have unknown interactive effects with psychoactive drugs and herbs. Bactericidal and bacteriostatic agents may reduce the inti-infective properties of this plant.
Additional Considerations: Should not be confused with cola acuminata which contains high amounts of caffeine.
Warnings: The information above is provided for educational purposes and may not be construed as a medical prescription or as a substitute for the advice of your physician. Do not use this product without first consulting your physician especially if you are pregnant or lactating. Be advised that some herbs and dietary supplements can cause severe allergic reactions in some individuals and may also have an adverse result in conjunction with other medications, or treatments. You should regularly consult your physician in matters regarding your health and particularly in respect to symptoms and conditions which may require diagnosis or medical attention. Reevaluate use of this product after 6 months.